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ubpbio/Non-cleavable K48 PolyUb Chain <sub>(2-6)</sub>/D1601/100 µg

ubpbio/Non-cleavable K48 PolyUb Chain <sub>(2-6)</sub>/D1601/100 µg
商品编号:
D1601
市场价:
¥5000.00
美元价:
3000.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
UbchainsareformedbyconjugatingtheC-terminalglycineresidueofUbontoanyofseveninternallysineresiduesortheaminogroupofthepreviousUb.UbchainsareclassifiedbythelysineresidueusedtolinkUbs;differentUbchaintopologiescanresultindifferentsignals.Forinstance,Ubchainslinkedthroughlysine6,11,27,29,33and48arecapableoftargetingproteinsforproteasomaldegradation;incontrast,Ubchainslinkedthroughlysine63ortheN-terminalaminogroup(linearUbchains)oftenplayimportantnonproteolyticfunctionsincludingregulationofkinaseactivationandproteintranslation.AllUbchainproductsareproducedbyusingofhumanwildtypeUbreactingwithspecificE2s.
Non-cleavableK48polyUbchainsaremadeoftheUb(L73P)mutant.
Non-cleavableK48polyUbchainsaremadeoftheUb(L73P)mutant.
AdditionalInformation
ProductName: | Non-cleavableK48PolyUbChain(2-6) |
---|---|
AlsoKnownAs: | N/A |
CatalogNo.: | D1601 |
Size: | 100µg |
MolecularWeight: | N/A |
Species: | Human |
Source: | Bacterialrecombinant |
Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
Concentration: | Seetubelabel |
QualityAssurance: | ~95%bySDS-PAGE,seedatasheetforgelimage |
Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
PDFDataSheet: | PDFDatasheet,MSDS |
NCBIRefSeq: | N/A |
Image(s): | N/A |
ShippingMethod: | Dryiceshipping |
References: | 1.HershkoA,etal.(1980)ProcNatlAcadSciUSA77(4),1783-1786. 2.PickartCM,(1997)FASEB11(13),1055-1066.3.HershkoA,etal.(1998)AnnRevBiochem67,425-479. 4.JiangX,etal.(2012)NatureReviewsImmunology12,35-48. |