
ubpbio/6xHis泛素(L73P)/E1940/1mg
商品编号:
E1940
市场价:
¥1500.00
美元价:
900.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Ubiquitin(Ub)isa76aminoacidproteinwidelyexpressedinthecytoplasmicandnucleusofcells.UbisposttranslationallyconjugatedtoproteinsbytheE1,E2,E3proteinubiquitinationcascade.UbcanbeconjugatedonproteinsasmonoUborpolyUbchains.Proteinubiquitinationplaysbothproteolyticandnonproteolyticfunctions.Usually,polyubiquitinatedproteinsaretargetedtothe26Sproteasomeforproteolysis.Typicalconcentrationtosupportinvitroubiquitinationis50-100µM.
StudieshaveshownthatpolyUbchainsformedbytheUb(L73P)mutantareresistanttodeubiquitinationcatalyzedbymanydeubiquitinationenzymes.
StudieshaveshownthatpolyUbchainsformedbytheUb(L73P)mutantareresistanttodeubiquitinationcatalyzedbymanydeubiquitinationenzymes.
AdditionalInformation
ProductName: | 6xHis-Ubiquitin(L73P) |
---|---|
AlsoKnownAs: | 6xHis-Ub(L73P) |
CatalogNo.: | E1940 |
Size: | 1mg |
MolecularWeight: | 8.5kDa |
Species: | Human |
Source: | Bacterialrecombinant |
Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
Concentration: | Seetubelabel |
QualityAssurance: | >95%bySDS-PAGE |
Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
PDFDataSheet: | PDFDatasheet,MSDS |
NCBIRefSeq: | N/A |
Image(s): | N/A |
ShippingMethod: | Dryiceshipping |
References: | 1.HershkoA,etal.(1980)ProcNatlAcadSciUSA77(4),1783–1786. 2.PickartCM(1997)FASEB11(13),1055–1066.3.HershkoA,etal.(1998)AnnRevBiochem67,425–479. 4.JiangX,etal.(2012)NatureReviewsImmunology12,35–48.5.BremmA,etal.(2012)MethodsMolBiol832,291–228. |