
ubpbio/GST-USP7/H5710/25µg
商品编号:
H5710
市场价:
¥3900.00
美元价:
2340.00
产品分类:
其它酶
公司分类:
Other_enzymes
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
USP7isacysteineprotease,belongstothefamilyofubiquitin-specificproteases.USP7wasfirstdiscoveredasabindingenzymetotheHerpessimplexviralprotein.StudieshaveshownthatUSP7coulddeubiquitinatetheautoubiquitinationofanE3
ligasecalledHDM2thatpromotesubiquitinationandsubsequentdegradationofp53.TheUSP7/HDM2/p53interactionresultsinhigherproteinlevelsofHDM2andlowerlevelsofp53.Becauseofitsapparentroleindifferenttypesofpathologies,includinglungandlivercancer,ithasbecomeapossIBLetargetfordrugtherapies.
ligasecalledHDM2thatpromotesubiquitinationandsubsequentdegradationofp53.TheUSP7/HDM2/p53interactionresultsinhigherproteinlevelsofHDM2andlowerlevelsofp53.Becauseofitsapparentroleindifferenttypesofpathologies,includinglungandlivercancer,ithasbecomeapossIBLetargetfordrugtherapies.
AdditionalInformation
ProductName: | GST-USP7 |
---|---|
AlsoKnownAs: | TEF1;HAUSP |
CatalogNo.: | H5710 |
Size: | 25µg |
MolecularWeight: | 128.3kDa |
Species: | Human |
Source: | Sf9insectcells |
Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
Concentration: | Seetubelabel |
QualityAssurance: | ~90%bySDS-PAGE,seedatasheetforgelimage |
Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
PDFDataSheet: | PDFDatasheet,MSDS |
NCBIRefSeq: | NM_003470 |
Image(s): | N/A |
ShippingMethod: | Dryiceshipping |
References: | 1.EverettRD,etal.(1997)EMBOJ16(7),1519–1530. 2.LiM,etal.(2004)MolCell26(13),879–886.3.CumminsJM,etal(2004)Nature428(6982),1pfollowing486. 4.NicholsonB,etal.(2011)CellBiochemBiophys60(1–2),61–68. |