ubpbio/ML323/F4120/5 mg
商品编号:
F4120
市场价:
¥1600.00
美元价:
960.00
产品分类:
酶抑制剂
公司分类:
Enzyme_Inhibitors
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ML323isacellpermealbe,selectiveandhighlypotentinhibitorofUSP1-UAF1withIC₅₀of76nMinaUb-Rhoassayand174nMand820nMinorthogonalgel-basedassaysusingK63-linkeddiubiquitin(di-Ub)andmonoubiquitinatedPCNA(Ub-PCNA)assubstrates,respectively.ML323effectivelysensitizedcisplatin-resistantNSCLCH596cellsandU2OSosteosarcomacellstocisplatinsinceitsimultaneouslytargetstwomajorDNAdamageresponsepathways(TLSandFA)byinhibitingUSP1-UAF1.
AdditionalInformation
ProductName: | ML323 |
---|---|
AlsoKnownAs: | N-(4-(1H-1,2,3-triazol-1-yl)benzyl)-2-(2-isopropylphenyl)-5-methylpyrimidin-4-amine |
CatalogNo.: | F4120 |
Size: | 5mg |
MolecularWeight: | 384.48Da |
Species: | N/A |
Source: | Synthetic |
Stock: | Powder |
Concentration: | N/A |
QualityAssurance: | >99%byHPLCandNMR |
Storage: | EligIBLeforroomtemperatureshipping.Storeat-20°Cuponreceiving;protectfromairandlight |
PDFDataSheet: | PDFDatasheet |
NCBIRefSeq: | N/A |
Image(s): | (Clickimagetoenlarge) PuritycheckofML323byHPLC |
ShippingMethod: | Roomtemperatureshipping |
References: | LiangQ,etal.(2014)NatChemBiol.10(4):298-304. |