ubpbio/ML323/F4121/25毫克
商品编号:
F4121
市场价:
¥6400.00
美元价:
3840.00
产品分类:
酶抑制剂
公司分类:
Enzyme_Inhibitors
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ML323isacellpermealbe,selectiveandhighlypotentinhibitorofUSP1-UAF1withIC₅₀of76nMinaUb-Rhoassayand174nMand820nMinorthogonalgel-basedassaysusingK63-linkeddiubiquitin(di-Ub)andmonoubiquitinatedPCNA(Ub-PCNA)assubstrates,respectively.ML323effectivelysensitizedcisplatin-resistantNSCLCH596cellsandU2OSosteosarcomacellstocisplatinsinceitsimultaneouslytargetstwomajorDNAdamageresponsepathways(TLSandFA)byinhibitingUSP1-UAF1.
AdditionalInformation
| ProductName: | ML323 |
|---|---|
| AlsoKnownAs: | N-(4-(1H-1,2,3-triazol-1-yl)benzyl)-2-(2-isopropylphenyl)-5-methylpyrimidin-4-amine |
| CatalogNo.: | F4121 |
| Size: | 25mg |
| MolecularWeight: | 384.48Da |
| Species: | N/A |
| Source: | Synthetic |
| Stock: | Powder |
| Concentration: | N/A |
| QualityAssurance: | >99%byHPLCandNMR |
| Storage: | EligIBLeforroomtemperatureshipping.Storeat-20°Cuponreceiving;protectfromairandlight |
| PDFDataSheet: | PDFDatasheet |
| NCBIRefSeq: | N/A |
| Image(s): | (Clickimagetoenlarge)![]() PuritycheckofML323byHPLC |
| ShippingMethod: | Roomtemperatureshipping |
| References: | LiangQ,etal.(2014)NatChemBiol.10(4):298-304. |


