ubpbio/Torin-1/F6100/5毫克
商品编号：
F6100
市场价：
¥1100.00
美元价：
660.00
产品分类：
酶抑制剂
公司分类：
Enzyme_Inhibitors
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Torin1-isacellpermeablehighlypotent,selectiveandATP-competitivemTORinhibitorofthemammaliantargetofrapamycin(mTOR)kinase.Torin-1exhibitsover100-foldselectivityformTORoverPI3KαandotherPI3K-likekinases,aswellas450otherproteinkinases.Torin-1hasbeenfoundtoimpaircellgrowthandproliferationthroughamechanisminvolvingmTORC1inhibitionotherthanmTORC2inhibition,inwhichtherapamycin-resistantfunctionsofmTORC1issuppressed.
AdditionalInformation
| ProductName: | Torin-1 |
|---|---|
| AlsoKnownAs: | 1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benzo[h]-1,6-naphthyridin-2(1H)-one |
| CatalogNo.: | F6100 |
| Size: | 5mg |
| MolecularWeight: | 607.62Da |
| Species: | N/A |
| Source: | Synthetic |
| Stock: | Powder |
| Concentration: | N/A |
| QualityAssurance: | >99%byHPLCandNMR |
| Storage: | EligIBLeforroomtemperatureshipping.Storeat-20°Cuponreceiving;protectfromairandlight |
| PDFDataSheet: | PDFDatasheet |
| NCBIRefSeq: | N/A |
| Image(s): | N/A |
| ShippingMethod: | Roomtemperatureshipping |
| References: | 1.GuertinDA,etal.(2009)Sci.Signal.2(67):pe24 2.ThoreenCC,etal.(2009)J.Biol.Chem.284(12):8023-32 3.LiuQ,etal.(2010)J.Med.Chem.53(19):7146-55 |
